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Hapless museum night watchman Larry Daley must help his living, breathing exhibit friends out of a pickle now that they've been transferred to the archives at the Smithsonian Institution. Larry's (mis)adventures this time include close encounters with Amelia Earhart, Abe Lincoln and Ivan the Terrible.

Ben Stiller

Larry Daley

Amy Adams

Amelia Earhart

Owen Wilson

Jedediah Smith

Hank Azaria

Kahmunrah / The Thinker / Abe Lincoln

Robin Williams

Theodore Roosevelt

Christopher Guest

Ivan the Terrible

Steve Coogan

Octavius

Ricky Gervais

Dr. McPhee

Bill Hader

General George Armstrong Custer

Jon Bernthal

Al Capone

Kai James

Teenage Boy #3

Mizuo Peck

Sacajawea

Rami Malek

Ahkmenrah

Crystal the Monkey

Dexter

Mindy Kaling

Docent

Jake Cherry

Nicky Daley

Alain Chabat

Napoleon Bonaparte

Patrick Gallagher

Attila the Hun

Jay Baruchel

Joey Motorola

Keith Powell

Tuskegee Airman #1

Craig Robinson

Tuskegee Airman #2

Clint Howard

Air and Space Mission Control Tech #1

Matty Finochio

Air and Space Mission Control Tech #2

Caroll Spinney

Oscar the Grouch

Eugene Levy

Albert Einstein Bobbleheads (voice)

Joe Jonas

Cherub #1 (voice)

Kevin Jonas

Cherub #2 (voice)

Nick Jonas

Cherub #3 (voice)

George Foreman

Himself

Shawn Levy

Infomercial Father

Alberta Mayne

Kissing Nurse

Ed Helms

Ed

Jonah Hill

Brundon

Ben Garant

Orville Wright

Thomas Lennon

Wilbur Wright

Shawn Levy

Directing

Shawn Levy

Production

Chris Columbus

Production

Thomas Lennon

Writing

Alan Silvestri

Sound

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